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Methadone also known as Dolophine among other opioids, which is sold under the brand names of
Methadose Oral Concentrate, Diskets, Westadone.
Methadone today is use to treat people with extreme pain. It has also been shown as part of a treatment
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Methadone is used for opioid maintenance therapy, to help with tapering in people with opioid
dependence, and for pain. A single dose has a rapid effect, maximum effect can take five days of use.
The pain relieving effects last about six hours after a single dose. So if you are taking more doses you
can imagine the how long it will take to relief your pain, these effect is similar to that of morphine. After
long term use, in people with normal liver function, effects last 8 to 36 hours. Methadone is usually taken
by mouth and rarely by injection into a muscle or vein.
It can also help if you’re in treatment for addiction to other opioids. It can give a similar feeling and
prevent withdrawal symptoms. Methadone replaces the opioids in your system with milder effects.

What Does It Do?
Methadone changes the way your brain and nervous system respond to pain so that you feel relief. Its
effects are slower than those of other strong painkillers like morphine. It blocks the high you get from
drugs like codeine, heroin, hydrocodone, morphine, and oxycodone.

Common site effects include dizziness, sleepiness, vomiting, and sweating

It is primarily a μ-receptor agonist and may mimic endogenous opioids, enkephalins, and endorphins and
affect the release of other neurotransmitters-acetylcholine, norepinephrine, substance P, and dopamine.
In the United States, methadone may be prescribed by physicians and dispensed by community
pharmacies for analgesia as a Schedule II drug under the regulations of the Controlled Substances Act.
Methadone is a federally designated Schedule II drug, meaning it has a legitimate legal use but also a
high likelihood of its users developing a dependence. Other Schedule II drugs include hydrocodone and
morphine.

Methadone is a depressant, and will cause a negative interactions when taken alon side with other drugs
like alcohol, which is also a depressant. Some people struggling with a methadone addiction are also
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Methadone may be habit-forming, even at regular doses. Never share this medicine with another person,
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